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Selecting the Best Medicinal Mushroom Extract

Sunday, November 8th, 2009    Subscribe To Our Feed

Medicinal mushrooms, hugely popular for thousands of years in the Orient, are coming in vogue today also in the West. On the coattails of their increasing popularity follow issues of quality and ethical representation between competing brands.

All medicinal mushroom species are plagued by this. Most fiercely debated is red reishi (Ganoderma lucidum), the most popular of all medicinal mushrooms. So this article will primarily focus on that species, but it’s generally applicable to all species of medicinal mushrooms.

An obvious caution is to stay away from cheap, mass-produced reishi. It may be merely dried and pulverized. In order to be medicinal, the mushroom cell-wall has to be broken down. Mass-produced reishi may be mostly inert and ineffective.

There are many real therapeutic brands on the market, though. But even among them, there are significant differences. They all claim to be the best, naturally, because they all want to sell their particular brand. So let’s sift the data, get the facts straight, and clear up misleading information that is out there.

There are primarily three ways to extract the medicinal compounds from red reishi. Each method pulls out different compounds, all of which have been proven by scientific research to be therapeutically important.

1. Water Extraction, Hot (polysaccharides and more)

2. Alcohol Extraction (triterpenoids, sterols)

3. Fermentation (arabinoxylanes, etc.)

The water soluble compounds, primarily polysaccharides, are powerful anti-tumor agents, immune enhancers and strong antioxidants. [1]

Through alcohol extraction, we get triterpenoids, a large group of lipids with many sub-groups. Research shows triterpenoids help regulate clotting, blood pressure and cholesterol. More importantly, they are the anti-inflammatory compounds that are the reason why reishi often gets recommended for arthritis, asthma and allergies. [1]

And then there are the new and unique medicinal compounds that get created when reishi is fermented. These “secondary metabolites” have their own therapeutic properties, different from the first two groups, including anti-tumor, immune support and blood-sugar balance. [2]

Since this article is not intended to elevate any one brand over another, no brand names will be mentioned. Nevertheless, the author does know of two highly reputed brands (American and Japanese) that claim only hot water extracted red reishi is of any value and that alcohol extracts are useless.

Naturally, the reason they say so is because they want to sell their own brand. However, those statements are scientifically untrue. Hot water and alcohol extractions both contain critical compounds.

To find the best red reishi products, look for those brands that use at least the first two extraction methods in combination: Hot Water Extraction and Alcohol Extraction. Better yet would be brands that incorporate all three extraction methods, including Fermentation.

Last but not least, remember to look at the form the reishi comes in. If the reishi is able to dissolve completely in water-based drinks like coffee, it’s a safe bet that it only contains the water-soluble polysaccharides. An excellent choice as far as coffee goes but an incomplete reishi supplement because it does not include the anti-inflammatory triterpenoid compounds.

Surprisingly, though, alcohol tinctures may include both hot water extract and alcohol extract. You will know if the alcohol tincture contains polysaccharides because when the alcohol and hot water extracts are blended, the polysaccharides fall out of solution and the tincture becomes cloudy. (Just shake it before you take it.) A cloudy medicinal mushroom tincture is an indication of high polysaccharide content. Capsules and tablets may be either hot water extract or alcohol extract or both.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L, 2007. “Ganoderma lucidum and its pharmaceutically active compounds.” Biotechnology Annu Rev 13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ. “Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum.” Bioresource Technology 2009 Mar;100(5):1852-9.

Dr. Rafael has worked with natural health since the early 90’s, currently focusing on medicinal mushrooms. He partners with Davida Sara on red reishi extract and cordyceps extract plus the newly popular mesima and many more.

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